How Long Does Tramadol Stay In Your System? 2022

How Long Does Tramadol Stay In Your System? Tramadol, like tilidine, is classified as a weakly effective opioid in the WHO Phased plan for pain therapy and is recommended for the treatment of moderate pain. Due to its low analgesic potency, the drug was previously considered a relatively safe opioid and was classified by the American Food and Drug Administration (FDA) in the drug category (Schedule) 4, which lists substances with a low risk of abuse and addiction. In the course of the US opioid crisis, tramadol was therefore often used as an alternative to the much stronger oxycodone or fentanyl. Now it seems as if the active ingredient has a much higher addiction potential than previously suspected. After all, more pain patients are asking for another prescription than for other opioids.

Why is Tramadol withdrawal necessary?

How Long Does Tramadol Stay In Your System? As a psychoactive substance, the synthetically produced opioid acts in the central nervous system of humans binds to the opioid receptors, and thereby influences the human neurotransmitter metabolism. Unfortunately, under the influence of the active ingredient, the natural pain regulation and the body’s own messengers get out of balance in the long run, and with prolonged use, even the slightest stimulus without the opioid can be perceived as severe pain.

Likewise, those affected have to take the drug in higher doses again and again in order to still feel the initial effect (tolerance development). The intake of tablets and drops determines the daily life of patients, and things that make life worth living are increasingly fading into the background.

How Long Does Tramadol Stay In Your System? At this point, it is important that the person concerned is accompanied by an experienced pain therapist. After all, there are definitely patients who become painless with Tramadol and therefore do not need to increase the dose. At the moment when there is an ever-increasing increase, the painkiller must be replaced by another, more suitable remedy. In addition, the practitioner must critically question whether the person concerned is increasing the dose because the tramadol no longer works for the pain, or because the patient longs for the intoxicating effect. This is lost during a long-term medication, while the pain-relieving effect is often retained.

What few people know: tramadol is the only opioid that has a positive effect on the serotonin balance, i.e. it improves mood. Here, a more accurate diagnosis and a more extensive anamnesis should be carried out in order to exclude a hidden depression, which, if necessary, can be treated more expediently by other medications.

How Long Does Tramadol Stay In Your System? Tramadol can also provoke strong side effects. Nausea and vomiting, dizziness and changes in appetite are among the more harmless undesirable effects. It becomes much more unpleasant for those affected if visual disturbances, impaired reactivity, allergic reactions, and hallucinations are added. In combination with other psychoactive drugs, other unpleasant side effects may occur, as well as questionable interactions. A tramadol dependence should therefore in no case be accepted permanently.

How Long Does Tramadol Stay In Your System?
How Long Does Tramadol Stay In Your System?

What preparations can be withdrawn during tramadol withdrawal?

The active substance tramadol is marketed in Germany under various trade names, including mono preparations and combination preparations with paracetamol. The most well-known single preparations include Tramal-long and Tramal; other trade names are Amadol, Jutadol, Tramagit, Tramundin, Travex, and Ultram. Bolivar and Zaldiar are marketed as combination preparations. Since it is about the withdrawal of the active substance, it does not matter for the tramadol withdrawal, however, which preparation it is.

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Why is a cold withdrawal of Tramadol not recommended?

How Long Does Tramadol Stay In Your System? Those who have been suffering from physical and psychological dependence for years often think that a cold withdrawal would be the best, fastest, and easiest way to stop the drug. In such a procedure, the addicted tablets and drops abruptly stop overnight. In general, the following withdrawal symptoms can occur with opiate withdrawal (varying degrees of severity depending on the type of opiate):

  • Inner unrest,
  • Be headaches,
  • Aches,
  • Nausea and vomiting,
  • Diarrhea and abdominal cramps,
  • Tremor,
  • increased pulse and blood pressure,
  • disturbed temperature regulation of the body,
  • Hyperventilation and
  • Feelings of fear.

Many tramadol addicts, therefore, fail on the first day and resort to their usual dose again in order to alleviate the tramadol withdrawal symptoms. As a result of this failed withdrawal attempt, there is often no motivation for further withdrawal, so that the person concerned becomes even more dependent in the long term and can be prescribed tramadol drops or tablets again and again by their doctor. If the doctor does not issue another prescription due to the risk of addiction, the nearest doctor is often visited to have enough tramadol on hand.

How does warm tramadol or tramadol withdrawal proceed?

If the treatment with tramadol no longer brings relief, but the tablets are taken only to alleviate the withdrawal symptoms, a qualified tramadol withdrawal is the only way back to a healthy life. Those affected can best take this step in a professional withdrawal clinic. There you do not have to stop taking the medication overnight but are gradually weaned from the effect of the drug by a continuous reduction in the dose, deal with the psychological causes of addiction after detoxification and receive a detailed follow-up plan for the time after tramadol withdrawal.

How Long Does Tramadol Stay In Your System?

How Long Does Tramadol Stay In Your System?
How Long Does Tramadol Stay In Your System?


How Long Does Tramadol Stay In Your System? In order to keep the stress for the body as low as possible and to bring the natural messenger metabolism gently and gently back into balance, the patients receive an individual dosage schedule in which the gradual reduction of the opioid is determined. The withdrawal symptoms are already significantly reduced by this fractional drug withdrawal. In addition, the attending physician may recommend a parallel medication to the clinic, which will help to additionally alleviate Tramadol withdrawal symptoms. This affects both the physical and psychological symptoms. Physical withdrawal is considered complete when all metabolic products (metabolites) are completely broken down. Sometimes, as already mentioned above, it also makes sense to integrate another medication into the patient’s medication plan in the long term, such as an antidepressant or another class of pain medication that has no dependence potential.


How Long Does Tramadol Stay In Your System? Pain that is not caused by a physical illness or dysfunctional impairments can often have psychological reasons. This is called psychosomatic pain. Since there are no physical causes, the medical diagnosis is accordingly difficult. These patients often undergo a diagnosis lasting for years with many cumbersome examinations without a result. This medical marathon is an additional burden and intensifies the symptomatology even more. It is becoming increasingly difficult for those affected to trust doctors and there is often a concern that they are suffering from a very rare serious illness that has only not yet been recognized.


In individual psychotherapeutic sessions, one should go in search of the reasons for the emergence of these psychosomatic ailments. In these cases, this is the best possible help for the desperate patient. With the understanding of the origin of the pain, they often dissolve or become significantly weaker. Some medications, such as the antidepressant amitriptyline, are used to treat both depression and pain, which is often an optimal addition to psychotherapy for psychosomatic patients.

In weaning therapy, the addict receives intensive psychotherapeutic treatment, which, depending on the institution, can consist of both individual and group therapies. The goal of therapy is to identify the causes of painkiller use, process them and replace them with more “healthy” solutions. Patients with chronic pain, for example, can find new ways to cope with the pain differently with the help of accompanying therapies such as acupuncture or sports offers.

How Long Does Tramadol Stay In Your System? If psychological reasons are the cause, it is important to become aware of them in the accompanying psychotherapy, so that an escape from the pain is no longer necessary. In addition, it is of course important to treat concomitant diseases such as depression or anxiety disorders medically, therapeutically, and sometimes with medication and to give the patient a much better attitude to life.

Outpatient follow-up therapy

Even if a withdrawal cure can last several weeks – at some point the inpatient stay in the clinic is over and the dependent returns to his own four walls. For many patients who have successfully combated the symptoms of the disease, this step is nevertheless associated with a queasy feeling. Although you learn new behavioral strategies in therapy that will help you not to have to take pain medication or other addictive substances in the future, you still feel unsure whether you will actually manage to stay strong.

And this is not wrong, because an opioid addiction, like any addiction, can never be completely cured by the addiction memory that has arisen, but can only be managed by a complete abstinence. In order to achieve this goal, it is recommended to accept appropriate offers of help after the hospital stay. These primarily include a visit to a follow-up therapist and participation in a self-help group.

What about the duration of a Tramal® withdrawal?

Anyone who has had to take Tramadol for years and now wants to slowly reduce the dosage as part of addiction therapy, understandably wonders how long the complete detoxification takes. However, a concrete specification of the tramadol withdrawal duration is not possible. Too many individual factors can influence the course of opioid withdrawal. In principle, however, in the case of a warm withdrawal, i.e. drug-assisted detoxification, and weaning, it is to be assumed that the patient will be hospitalized for several weeks.

How Long Does Tramadol Stay In Your System? The choice of the addiction clinic also plays a major role. Thus, the withdrawal in public institutions takes place in two separate steps and facilities, so a total treatment period of several months must be assumed here. Detoxification in a hospital or a psychiatric hospital usually takes 4 weeks alone and is completely decoupled from the actual weaning treatment, which is absolutely and absolutely necessary for maintaining longer-term abstinence. In addition, weaning/addiction rehabilitation must first be applied for pension insurance. The patient usually waits for 3 to 6 weeks for the cost commitment of the pension insurance and often relapses during this time. The weaning therapy then usually lasts about 12 weeks, i.e. 3 months.

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How Long Does Tramadol Stay In Your System? If the withdrawal takes place in a private clinic, the detoxification and weaning treatment is carried out in a common treatment block and takes place with the same doctors and therapists. There is no interim waiting time. In addition, the withdrawal usually takes place much more intensively, so overall a shorter period of time can be assumed than in public institutions. At the My Way Betty Ford Private Clinic in Bad Brückenau, for example, the patient receives 5 individual therapy and group sessions a week. This corresponds to complete short-term therapy, for which you need about 1 year in an outpatient setting with a psychologist. The duration of treatment in the clinic, depending on the narcotic substance, is usually only 4 to 6 weeks.

What Tramadol withdrawal symptoms are to be expected?

How Long Does Tramadol Stay In Your System? People who take tramadol or other opioid painkillers for a long time often noticed physical and psychological withdrawal symptoms even with a slight change in the dose. The very thought of reducing the intake of Tramadol causes panic in many sufferers. Typical side effects of withdrawal from tramadol or other opiates and opioids include:

  • Nausea, diarrhea, and vomiting
  • Changes in appetite
  • Sleep problems
  • Depressive moods
  • Tremors and sweats
  • Inner unrest
  • Muscle cramps and muscle pain
  • Abdominal cramps
  • increased pulse and blood pressure
  • disturbed temperature regulation of the body
  • Feelings of fear
  • Hyperventilation

When and how are relatives involved in therapy?

How Long Does Tramadol Stay In Your System? If pain patients have been taking painkillers for a long time and have developed an addiction as a result, in most cases this is accompanied by social and private consequences. Family members such as spouses, parents, or children have directly experienced the problems and consequences of dependence. This makes it all the more important that they are given the opportunity to work through the effects of the disease professionally.

How Long Does Tramadol Stay In Your System? However, the work of relatives is not only about the relatives themselves but also about the addict. Anyone who is dependent on medication, alcohol, or drugs must be able to count on a stable environment after the successful completion of their therapy in order not to relapse again. For this, family relationships or problems sometimes have to be worked out. In order to achieve this, it is possible in some clinics to involve close relatives in individual therapy sessions. This procedure is advisable in many cases but always remains optional.

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